Question

All of the following statement regarding DNA replication is FALSE?

a
A primer is required for Primase.
b
A primer is required for DNA polymerase.
c
The processivity of DNA polymerase is increased via the Sliding Clamp.
d
Removal of the RNA primer is performed by a Nuclease, which is then replaced with DNA via the activity of a DNA repair polymerase.

Answer 1

In DNA replication, a primer is not required for Primase. Primase synthesizes RNA primers that are needed for DNA polymerase to start adding nucleotides. The RNA primers are later replaced with DNA nucleotides by the activity of a DNA repair polymer-ase.

Step-by-step explanation:

In DNA replication, a primer is required for Primase, which is a false statement. Primase actually synthesizes RNA primers that are needed for DNA polymerase to start adding nucleotides. The RNA primers are later replaced with DNA nucleotides by the activity of a DNA repair polymerase.