Final answer:
If nuclease activity were deficient in a cell line, the abnormality you might expect in the replicated DNA is the presence of unfinished or fragmented DNA strands.
Step-by-step explanation:
If nuclease activity were deficient in a cell line, an abnormality you might expect in the replicated DNA is the presence of unfinished or fragmented DNA strands. Nucleases are enzymes responsible for breaking down DNA. Therefore, without adequate nuclease activity, the DNA replication process may be incomplete, leading to DNA fragments that cannot be properly joined together. This can result in errors in the DNA sequence and potential genetic abnormalities.