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Which blood types could be passed to offspring from the following biological parents?

Male: AB+
Female: O-

User Glebcom
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Final answer:

A male with AB+ blood and a female with O- blood can have offspring with either blood type A (IAi) or B (IBi) but not blood type O (ii) or AB (IAIB). The Rh factor can be positive or negative.

Step-by-step explanation:

From the given pair of biological parents, where the male is AB+ (genotype IAIB) and the female is O- (genotype ii), the possible blood types that could be passed to their offspring are A (genotype IAi) and B (genotype IBi). Since the mother has type O blood, she can only pass on the recessive 'i' allele. The father, having type AB blood, can pass on either the IA or IB allele. The offspring cannot have type O blood, as they will receive at least one dominant allele from the father. It is also impossible for the child to have AB blood type, as they would require a dominant allele from each parent. The Rh factor is separate, but since the female is Rh- and only the male contributes to this, the offspring can be either Rh+ or Rh-.

The ABO blood group inheritance displays a pattern where A and B alleles are codominant, meaning an individual with both IA and IB alleles will express type AB blood. Blood type O occurs when a person inherits two recessive 'i' alleles and expresses no A or B antigens. Understanding this, we can conclude the potential blood groups that could result from this parental combination.

User Pusle
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