Final answer:
The heat-shock response in E. coli is mediated by heat shock proteins (HSP) that help the cell refold misfolded proteins in response to increased temperature.
Step-by-step explanation:
The heat-shock response in E. coli is mediated by heat shock proteins (HSP). Heat shock proteins help the cell refold misfolded proteins and are activated in response to increased temperature. When a heat shock occurs, heat shock proteins are released from the nuclear receptor/HSP complex and transcription of HSP genes is activated. This response helps the cell maintain proper protein function and structure under heat stress.