Question

What is the most common route of formation of primary cholesteatoma?

1) Migration of epithelial debris from the ear canal into the middle ear
2) Congenital abnormality in the development of the ear
3) Infection and inflammation of the tympanic membrane
4) Blockage of the Eustachian tube causing pressure build-up in the middle ear

Answer 1

Option 4). The most common cause of primary cholesteatoma formation is the blockage of the Eustachian tube, leading to pressure build-up and fluid accumulation in the middle ear, which provides a breeding ground for infections that can contribute to the development of cholesteatoma.

Step-by-step explanation:

The most frequent cause of primary cholesteatoma formation is frequently middle ear pressure buildup brought on by occlusion of the Eustachian tube. This obstruction may result in otitis media with effusion (OME), a build-up of fluid that fosters the growth of microorganisms. Prolonged infections may result in inflammation that blocks the Eustachian tube even more, creating an environment that is conducive to the growth of a cholesteatoma. Acute otitis media (AOM) is a disorder marked by an infection-related build-up of pus in the middle ear. If this fluid is not properly drained, a persistent build-up may eventually lead to cholesteatoma.