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What does the degenerate/promiscuous binding of MHC molecules allow?

User Mrapacz
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Final answer:

The degenerate/promiscuous binding of MHC molecules enhances immune system adaptability by enabling recognition of a wide range of antigens, thereby aiding in the activation of appropriate T cell responses against diverse pathogens.

Step-by-step explanation:

The degenerate/promiscuous binding of MHC molecules allows for a broad recognition of antigenic peptides, contributing to the diversity and adaptability of the immune response. This enables MHC molecules, particularly MHC I and MHC II, to present a wide variety of antigens to T cells, ensuring that the immune system can respond to a vast array of pathogens.

The adaptive immune system relies on this capability to activate and produce T cells tailored to effectively recognize and destroy invading pathogens. Infected or tumor cells that alter MHC I expression are identified by NK cells as abnormal, triggering an immune response.

User Jabda
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