Final answer:
Each amino acid in a polypeptide is connected by peptide bonds, not phosphodiester bonds, formed through dehydration synthesis.
Step-by-step explanation:
The statement that each amino acid in a polypeptide is connected through phosphodiester bonds is false. Instead, amino acids are linked together by a type of covalent bond known as a peptide bond. This bond forms through a dehydration synthesis reaction, where the carboxyl group of one amino acid reacts with the amino group of another, releasing a water molecule. This results in a peptide or polypeptide chain, where the sequence of amino acids determines the protein's characteristics.