Question

Which of the following adaptor proteins activate the NF-κB pathway?

A. MyD88
B. IKKα
C. Calmodulin
D. IL-2 receptor
E. SOS

Answer 1

The adaptor protein that activates the NF-κB pathway is MyD88.

Step-by-step explanation:

The adaptor protein that activates the NF-κB pathway is MyD88.

The NF-κB pathway is a signaling pathway that controls the expression of genes involved in immune response, cell survival, and inflammation. MyD88 is an adaptor protein that plays a key role in the activation of the NF-κB pathway.

Upon stimulation by specific ligands, such as Toll-like receptors (TLRs) or interleukin-1 receptors (IL-1Rs), MyD88 recruits and activates a protein complex that leads to the activation of NF-κB, resulting in the expression of target genes.