Question

Where would you MOST likely find a TLR that recognizes RNA?

A. On the cell surface
B. In the endosome/lysosome
C. In the nucleus
D. In the mitochondria
E. In the endoplasmic reticulum

Answer 1

TLRs that recognize RNA are most likely found in the endosome/lysosome compartments of a cell, where they help trigger an immune response upon detecting viral RNA.

Step-by-step explanation:

The TLRs (Toll-like receptors) that recognize RNA are most likely found in the endosome/lysosome of a cell. This is because RNA from viruses is typically recognized within these intracellular compartments rather than at the cell surface. Endosomes and lysosomes provide an environment where viral RNA can be detected by TLRs without causing harm to the cell, triggering an immune response if pathogenic RNA is recognized.