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Which electron microscope technique involves striking a frozen specimen with a knife-edge, cracking the ice of the tissue block that spread from the point of contact and

interact with tissue?

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Final answer:

Cryo-ultramicrotomy is the electron microscope technique that involves striking a frozen specimen with a knife-edge to crack the ice and interact with tissue. It is used to prepare specimens for the Transmission Electron Microscope (TEM).

Step-by-step explanation:

The electron microscope technique that involves striking a frozen specimen with a knife-edge to crack the ice and interact with tissue is called cryo-ultramicrotomy. This technique is used to prepare specimens for the Transmission Electron Microscope (TEM). In cryo-ultramicrotomy, the specimen is frozen and then sectioned using an ultramicrotome to obtain thin slices for electron microscopy.

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