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Where and when do endosomes become lysosomes?

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Final answer:

Endosomes become lysosomes when the vesicle merges with an early endosome to form a sorting vesicle, where digestive enzymes catalyze the hydrolysis of the vesicle contents.

Step-by-step explanation:

Endosomes become lysosomes when the vesicle that remains, now a lysosome, merges with an early endosome to form a sorting vesicle. In this vesicle, digestive enzymes catalyze the hydrolysis of the vesicle contents. The digest products are then released for cellular use.

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