Final answer:
A conformational epitope is formed as a result of the three-dimensional folding of a protein and is destroyed if the protein denatures.
Step-by-step explanation:
The protein epitope formed as a result of three-dimensional folding of the protein, and which is destroyed if the protein denatures, is called a conformational epitope.
Protein folding refers to the process by which a polypeptide chain assumes a three-dimensional shape. The folding is necessary for the biological activity of proteins. A protein's tertiary structure is its unique three-dimensional shape, which is maintained by side chain interactions.