Final answer:
Ig chains require transport vesicles to move from the ER to the Golgi apparatus, where they undergo modifications including glycosylation, before moving to the plasma membrane to become integral membrane proteins.
Step-by-step explanation:
Immunoglobulin (Ig) chains enter the endoplasmic reticulum (ER) as they are synthesized. They then associate with each other to form Ig molecules that are attached to the ER membrane. These molecules by themselves are unable to transport to the cell surface and thus require the help of transport vesicles for movement. The process involves the molecules being encapsulated into vesicles that bud off from the ER and subsequently fuse with the cis face of the Golgi apparatus.
Within the Golgi, the Igs undergo further modifications such as glycosylation, after which they are transported in vesicles that bud off from the trans face of the Golgi to the plasma membrane, where they finally become integral membrane proteins.