Final answer:
The two formal terms used to describe categories of mutational nucleotide substitutions in DNA are C) transversions and transitions. Hence, C) is correct.
Step-by-step explanation:
The two formal terms used to describe categories of mutational nucleotide substitutions in DNA are transversions and transitions.
Transitions refer to a purine or pyrimidine being replaced by a base of the same kind, while transversions refer to a purine being replaced by a pyrimidine, or vice versa.