Question

Adenine methylase is an enzyme used during mismatch repair (MMR). It helps determine which strand needs

to be repaired by discriminating between template and new DNA strand. If this enzyme is mutated, how would
MMR be affected?
A) MMR would not be hindered because adenine methylase is not directly involved in MMR.
B) MMR would be hindered because both strands would be unmethylated and both would appear as
template DNA strands.
C) MMR would be hindered because both strands would be overmethylated and both would appear as
template DNA strands and it would not be possible to determine which strand has the mutation.
D) MMR would be hindered because both strands would be unmethylated and both would appear as new
DNA strands and it would not be able to determine which strand has the error.
E) MMR would be hindered because both strands would be overmethylated and both would appear as new
DNA strands and it would not be able to determine which strand has the error.

Answer 1

If the adenine methylase enzyme used during mismatch repair (MMR) is mutated, MMR would be hindered because both strands would be unmethylated and both would appear as new DNA strands, making it difficult to determine which strand has the error.

Step-by-step explanation:

Adenine methylase is an enzyme used during mismatch repair (MMR). It helps determine which strand needs to be repaired by discriminating between the template and the new DNA strand. If this enzyme is mutated, MMR would be hindered because both strands would be unmethylated and both would appear as new DNA strands. This would make it difficult to determine which strand has the error that needs to be repaired.