Final answer:
The order release for Week 3 will be 0.
Step-by-step explanation:
To determine the order release for Week 3, we need to consider the manufacturing lead time of two weeks. The on-hand inventory at the end of Week 4 is 450, and the demand in Week 5 is 375. This means that the order release for Week 3 should be equal to the demand in Week 5 minus the on-hand inventory at the end of Week 4, which is 375 - 450 = -75. However, the order release cannot be negative, so the correct option would be: