Final answer:
The interaction between the ER signal sequence on a growing polypeptide chain and the signal recognition particle (SRP) guides the ribosome and its polypeptide to the ER membrane.
Step-by-step explanation:
The interaction between the ER signal sequence on a growing polypeptide chain and the signal recognition particle (SRP) guides the ribosome and its polypeptide to the ER membrane.
This interaction is important for the proper targeting and insertion of the polypeptide into the rough endoplasmic reticulum (RER), where it undergoes modifications and folding.