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RNA pol III: Which of the following complexes contains a zinc finger DNA binding domain?

-TFIIIB
-TFIIIC
- UBF1
-TFIIIA
-SL1

1 Answer

1 vote

Final answer:

TFIIIA is the transcription factor among the listed options that contains a zinc finger DNA binding domain, essential for the RNA polymerase III system in eukaryotes.

Step-by-step explanation:

The question pertains to the role of transcription factors in the RNA polymerase III system and which of them has a zinc finger DNA binding domain. Among the options listed in the question, TFIIIA is known to contain a zinc finger motif that allows it to bind to DNA. In eukaryotic transcription, various transcription factors, each denoted by 'TFII' followed by a different letter, recruit RNA polymerase to a gene's promoter to form the transcription initiation complex. TFIIIA's role is particularly important in the transcription of 5S rRNA genes by RNA polymerase III.

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