Question

In the telomere, the 3'-end is single-stranded with a 14-16 base overhang. There are two reasons for this. The first is that the G-T strand (3'€™-end) is extended by the telomerase enzyme. What is the second reason?

-G quartets form and expose more of the 3-end.
-POT1 extends the G-T strand (3-end).
-TRF2 exonuclease chews back the 5end.
-T-loops form and hide the 3-end.
-The C-A strand (5-end) is enzymatically degraded.

Answer 1

The second reason for the 3'-end of the telomere being single-stranded with a 14-16 base overhang is that T-loops form and hide the 3'-end.

Step-by-step explanation:

The second reason for the 3'-end of the telomere being single-stranded with a 14-16 base overhang is that T-loops form and hide the 3'-end.