Question

Role of TFIID versus SAGA (yeast) or PCAF (mammals): Which of the following statements is FALSE?

-Approximately 10% of yeast promoters use SAGA.
-90% of yeast promoters are TATAA-less and therefore use TFIID.
-SGA has subunits that allow it to recognize TATAA-less promoters.
-10% of yeast promoters contain a TATAA and these are often environmentally inducible

Answer 1

The false statement is that SGA has subunits that allow it to recognize TATAA-less promoters.

Step-by-step explanation:

The false statement is: SGA has subunits that allow it to recognize TATAA-less promoters.

SAGA is a co-activator complex in yeast that helps to regulate gene expression. Approximately 10% of yeast promoters use SAGA, while the majority of yeast promoters (90%) are TATAA-less and therefore use TFIID. TFIID is a transcription factor complex that recognizes TATA-less promoters.

TFIID recognizes TATAA-less promoters through its subunit called TBP (TATA-binding protein), which binds to the core promoter region and recruits other transcription factors for transcription initiation.