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Which of the following complexes acts as the "commitment factor" to specify the startpoint for RNA polymerase I transcription?

- B
-Brf
-TFIIIC
-UBF1
-SL1

User Sidd Thota
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Final answer:

The 'commitment factor' for specifying the start point for RNA polymerase I transcription is the SL1 complex.

Step-by-step explanation:

The complex that acts as the "commitment factor" to specify the start point for RNA polymerase I transcription is SL1.

In eukaryotic transcription, various transcription factors and complexes are involved in the initiation of transcription by RNA polymerase I, II, and III.

Specifically, RNA polymerase I transcription is initiated when the SL1 complex, along with the Upstream Binding Factor (UBF), binds to the core promoter region to form the pre-initiation complex. This marks the commitment of the complex to initiate transcription.

The initiation complex, in general, is a combination of transcription factors and RNA polymerase bound to a promoter.

User Pedro Penna
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