Final answer:
During meiosis, translocated chromosomes segregating to opposite poles from normal chromosomes may lead to aneuploid gametes, containing an abnormal number of genes.
Step-by-step explanation:
When normal chromosomes move to one pole and the translocated chromosomes to the other during meiosis, this can result in the production of aneuploid gametes. These gametes may have a missing or extra set of genes due to the unequal segregation of genetic material.
During meiosis, homologous chromosomes segregate to reduce the number of chromosome sets from two to one in a process called reduction division, resulting in haploid cells. However, structural rearrangements like translocations can complicate this process. If homologous chromosomes with translocations don't align correctly, it could lead to improper recombination and the formation of gametes with an incorrect number of genes, potentially causing genetic disorders.