Question

Chromosomal breaks (double-stranded DNA breaks) can reattach, but sometimes this happens in the reverse orientation, leading to an ____ or on different ____.

Answer 1

Chromosome inversions occur when a part of a chromosome detaches, rotates 180 degrees, and reinserts in the opposite orientation. This can result in a change in the gene orientation, but typically does not cause deletions or duplications of genetic information.

Step-by-step explanation:

Chromosome inversions occur when a part of a chromosome detaches, rotates 180 degrees, and reinserts in the opposite orientation. This can result in a change in the gene orientation, but typically does not cause deletions or duplications of genetic information. However, altered gene orientation can lead to functional changes due to regulators of gene expression being moved out of position with respect to their targets, resulting in aberrant levels of gene products.