Final answer:
The wobble hypothesis states that the third nucleotides of triplet codes are more flexible than the first two.
Step-by-step explanation:
The wobble hypothesis states that the third nucleotides of triplet codes are more flexible than the first two. This flexibility allows for a change in the third base by a mutation while still incorporating the correct amino acid into a protein.
The first two bases of each codon are more specific in determining the amino acid, while the third base is less critical and can vary.