Question

Which of the following is NOT a function of the initiation factors associated with translation of protein from mRNA?

A) They bind to the CAP group at the 5' end.
B) They form a complex with small ribosomal subunits.
C) They form a complex with charged tRNA.
D) They align the first tRNA with the P site on a ribosome.
E) They trigger binding of the small ribosomal subunit to AUG.

Answer 1

The initiation factors associated with translation of protein from mRNA have several functions, but triggering the binding of the small ribosomal subunit to AUG is not one of them.

Step-by-step explanation:

The initiation factors associated with translation of protein from mRNA have several functions, but one of the options listed is NOT a function. Let's go through each option:

1. They bind to the CAP group at the 5' end. This is true and helps the small ribosomal subunit recognize the start of the mRNA.
2. They form a complex with small ribosomal subunits. This is true and helps the ribosome assemble and start translation.
3. They form a complex with charged tRNA. This is also true and helps position the tRNA correctly during translation.
4. They align the first tRNA with the P site on a ribosome. This is also true and helps start the polypeptide chain.
5. They trigger binding of the small ribosomal subunit to AUG. This is NOT a function of the initiation factors. The binding of the small ribosomal subunit to AUG is a result of the initiation factors' actions, not a function of the initiation factors themselves.

Therefore, option E is the correct answer, as it is NOT a function of the initiation factors associated with translation of protein from mRNA.