Question

Chondrodysplasia in domesticated dogs is the result of:

a) Dogs hybridizing with polyploid wolves to produce a mutant offspring
b) Genome duplication in some dog breeds
c) A point mutation leading to the disorder in affected dog breeds
d) A processed mRNA inserted into the middle of a transposable element

Answer 1

Chondrodysplasia in dogs is caused by a point mutation in a specific gene affecting the breeds prone to the disorder, not by chromosomal abnormalities or hybridizations.

Step-by-step explanation:

Chondrodysplasia in domesticated dogs is the result of c) A point mutation leading to the disorder in affected dog breeds. This type of mutation can change an amino acid sequence in a protein, which can alter the protein's structure and function, potentially leading to a genetic disorder. In contrast, some genetic disorders are caused by an incorrect number of chromosomes, such as Down syndrome, caused by three copies of chromosome 21. However, in the case of chondrodysplasia in dogs, it is a single-gene mutation rather than a chromosomal abnormality that is responsible for the condition.