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The following happens when a G-protein-coupled receptor activates a G protein.

A) The B subunit exchanges its bound GDP for GTP.
B) The GDP bound to the a subunit is phosphorylated to form bound GTP.
C) The a subunit exchanges its bound GDP for GTP.
D) It activates the a subunit and inactivates the By complex.

User Danielson
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Final answer:

When a G-protein-coupled receptor activates a G protein, the α subunit exchanges its bound GDP for GTP, leading to activation and subsequent signaling events within the cell.

Step-by-step explanation:

The question pertains to what happens when a G-protein-coupled receptor activates a G protein. In this process, the correct event is that the α subunit exchanges its bound GDP for GTP (Option C). When a signaling molecule binds to the G-protein-coupled receptor, the α subunit releases guanosine diphosphate (GDP) and acquires guanosine 5'-triphosphate (GTP), resulting in the activation of the G protein.

Upon GTP binding, the G-protein subunits dissociate into the α subunit and the βγ complex. The α subunit or the dissociated βγ pair may then activate other proteins within the cell. After some time, the GTP on the active α subunit is hydrolyzed back to GDP, deactivating both the α subunit and the βγ complex, and the subunits reassociate to form the inactive G-protein, ready to start the cycle anew.