Final answer:
True. In the chronic phase of HIV infection, CD4 T-cell counts decrease continually.
Step-by-step explanation:
True. In the chronic phase of HIV infection, CD4 T-cell counts decrease continually. The decline in CD4 T-cell counts is a hallmark of HIV infection and is a key indicator of disease progression. As the number of CD4 T cells decreases, the immune system becomes weaker, making the individual more susceptible to opportunistic infections.
During the chronic phase, the level of HIV in the blood remains high, and the virus continues to replicate and infect new CD4 T cells. This ongoing replication and destruction of CD4 T cells lead to a progressive decline in their numbers over time.