Question

Which of the following does NOT occur shortly following oligomerization of the BCR upon antigen binding?

A. Movement of the BCR complex into areas of the membrane called "lipid rafts"
B. Positioning of Iga and Igß to allow for phosphorylation of their ITAM motifs
C. Positioning of CD3 to allow for phosphorylation if its ITAM motifs
D. Formation of clathrin-coated pits around BCR complex
E. All of the above occur.

Answer 1

The correct answer is D. Formation of clathrin-coated pits around BCR complex.

Step-by-step explanation:

The correct answer is D. Formation of clathrin-coated pits around BCR complex.

Following oligomerization of the BCR upon antigen binding, several events take place:

1. Movement of the BCR complex into areas of the membrane called "lipid rafts"
2. Positioning of Iga and Igß to allow for phosphorylation of their ITAM motifs
3. Positioning of CD3 to allow for phosphorylation if its ITAM motifs
4. Formation of clathrin-coated pits around BCR complex does NOT occur shortly following oligomerization of the BCR upon antigen binding