Final answer:
Some tumor cells in women contain inactivated X chromosomes with duplicated or deleted XIST genes, suggesting that the XIST gene is not required to maintain X chromosome inactivation.
Step-by-step explanation:
The evidence that suggests the XIST gene may not be required to maintain X chromosome inactivation from one generation to another is that some tumor cells in women contain inactivated X chromosomes whose XIST gene has been duplicated or deleted. This indicates that the XIST gene is not necessary for maintaining X chromosome inactivation. Additionally, the fact that tumor cells do not maintain X chromosome inactivation from generation to generation also supports the idea that the XIST gene is not essential for maintaining this process.