197k views
1 vote
Which of the following factors is thought to induce expression of Blimp-1?

A. Blimp-1
B. IRF-4
C. Pax-5
D. Bcl-6
E. NF-?B

1 Answer

2 votes

Final answer:

NF-κB induces the expression of Blimp-1 by dissociating from its inhibitor through phosphorylation, which allows it to enter the nucleus and stimulate transcription.

Step-by-step explanation:

The factors thought to induce the expression of Blimp-1 include NF-κB. NF-κB is known to stimulate transcription by entering the nucleus after the dissociation of its inhibitor IκB through phosphorylation. It does not typically involve binding with a hydrophobic ligand for its activation; however, it is a transcription factor that, when released into the nucleus, can promote protein production and induce gene expression relevant to immune responses and inflammation.

User Waley Chen
by
7.9k points