46.8k views
4 votes
Which of the following is considered to be the "master regulator" of terminal plasma cell differentiation?

A. Blimp-1
B. IRF-4
C. Pax-5
D. Bcl-6
E. NF-κB

User Fatuhoku
by
7.6k points

1 Answer

5 votes

Final answer:

The "master regulator" of terminal plasma cell differentiation is Blimp-1. Blimp-1 is a transcription factor that plays a critical role in the differentiation of B cells into plasma cells.

Step-by-step explanation:

The "master regulator" of terminal plasma cell differentiation is Blimp-1. Blimp-1 is a transcription factor that plays a critical role in the differentiation of B cells into plasma cells. It suppresses the expression of genes that promote B cell identity and activates genes involved in plasma cell function, such as antibody production.

User David Cummins
by
8.0k points
Welcome to QAmmunity.org, where you can ask questions and receive answers from other members of our community.