Final answer:
Mitochondria and chloroplasts each have their own genome, separate from the cell's nuclear genome, hence C. Both A and B is the correct answer.
Step-by-step explanation:
The organelles that have genomes separate from the genome in the cell nucleus are mitochondria and chloroplasts. Each of these organelles contains its own DNA, which is different from the nuclear DNA. In eukaryotic cells, the genomes consist of DNA housed in the nucleus and extrachromosomal DNA found specifically in the mitochondria for all eukaryotic cells and additionally in the chloroplasts for plants and algae.
Comparatively, the endoplasmic reticulum does not have its own genome; it is an organelle involved in protein synthesis and folding, as well as lipid metabolism, but it is dependent on the DNA found in the cell's nucleus for the instructions on how to perform these functions. Therefore, the correct answer to the question is C. Both A and B.