Final answer:
The voltage change caused by the Na+ currents through the open voltage-gated channels causes depolarization of the cell membrane.
Step-by-step explanation:
The voltage change caused by the Na+ currents through the open voltage-gated channels causes depolarization of the cell membrane. When an action potential is initiated at the beginning of the axon, Na+ ions enter the cell through the voltage-gated Na+ channels, causing depolarization of a small portion of the cell membrane. This depolarization spreads along the axon as more voltage-gated Na+ channels open and more Na+ ions rush into the cell, propagating the action potential.