Question

Which of the following do you expect would be actively functioning in a B cell that had migrated to a germinal center?

A. RAG-1
B. Artemis
C. AID
D. Ku70
E. None of the above

Answer 1

A B cell that has migrated to a germinal center would have AID actively functioning.

Step-by-step explanation:

In a B cell that has migrated to a germinal center, AID (Activation-Induced Cytidine Deaminase) would be actively functioning. AID is an enzyme that plays a crucial role in the somatic hypermutation and class switch recombination during B cell maturation in the germinal center.

It is responsible for introducing mutations in the immunoglobulin genes, leading to the generation of highly diverse antibodies with increased affinity for antigens. Therefore, the correct answer is C. AID.