Final answer:
Sympathetic stimulation of cholinergic fibers in the arterioles of skeletal muscle typically leads to vasodilation, which is a response aimed at increasing blood flow during fight-or-flight situations.
Step-by-step explanation:
When sympathetic stimulation occurs in the arterioles of skeletal muscle, it will typically produce vasodilation. This is an exception to the typical vasoconstriction response seen with most sympathetic stimuli. In skeletal muscles, especially in the lower limbs, this vasodilation facilitates increased blood flow, thereby enhancing muscle activity in response to fight-or-flight situations. Rather than using norepinephrine, these postganglionic sympathetic fibers release acetylcholine (ACh), leading to the activation of muscarinic receptors and subsequent vasodilation.