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The histone proteins that constitute the core nucleosome include tetramers of histone H2A, H2B, H3, and H4.

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Final answer:

Histone proteins form the core nucleosome, which includes tetramers of histone H2A, H2B, H3, and H4. This structure is known as the "beads on a string". The nucleosomes are further compacted into a 30 nm fiber.

Step-by-step explanation:

The histone proteins that constitute the core nucleosome include tetramers of histone H2A, H2B, H3, and H4. This is also known as the "beads on a string" structure. The negatively charged DNA is tightly wrapped around the histone core, and the nucleosomes are further compacted into a 30 nm fiber. At the metaphase stage, the chromosomes are highly compact and found in association with scaffold proteins.

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