Final answer:
When a germ cell fails to divide after DNA replication, it can result in a condition called nondisjunction, which can lead to gametes with an abnormal chromosome number.
Step-by-step explanation:
When a germ cell fails to divide after DNA replication, it can result in a condition called nondisjunction. Nondisjunction can occur during meiosis, the process of cell division that creates gametes (sperm and eggs). If homologous chromosomes fail to separate during meiosis I, it can lead to gametes that lack that particular chromosome or gametes with two copies of the chromosome. If sister chromatids fail to separate during meiosis II, it can result in gametes with an abnormal chromosome number, such as one gamete lacking the chromosome, two normal gametes with one copy of the chromosome, and one gamete with two copies of the chromosome.