Final answer:
MHC-based mate preference in human females refers to the tendency of females to prefer mates with different MHC genes than their own. This preference is believed to promote genetic diversity and improve the immune response of offspring. Research suggests that olfactory cues may be used to detect MHC differences in potential mates.
Step-by-step explanation:
MHC-based mate preference in human females refers to the tendency of females to prefer mates with different major histocompatibility complex (MHC) genes than their own. MHC genes play a role in the immune system, and it is believed that mate preference for different MHC genes may promote genetic diversity and improve offspring's immune response.
Research conducted by David M. Buss in 1989 suggested that females may exhibit this preference in order to choose mates who can provide genetic advantages to their offspring. The preference for different MHC genes may be detected through olfactory cues, as MHC genes influence body odor.
Overall, MHC-based mate preference in human females is thought to be an evolutionary strategy to increase genetic diversity and enhance the immune system of offspring.