Question

As a cell proceeds through mitosis, the amount of cohesion bound to sister chromatids changes. Place the descriptions of cohesion binding in order from earlier in mitosis at the top to later in mitosis (anaphase) at the bottom.

Answer 1

The correct order of events during mitosis concerning cohesion binding and sister chromatid separation starts with the kinetochore attaching to the mitotic spindle, followed by the chromatids aligning, the cohesin breaking down, and finally the cell dividing after the nucleus reforms.

Step-by-step explanation:

The question deals with the events of mitosis and particularly the behavior of cohesin proteins and their role in sister chromatid separation. Mitosis has distinct phases that must follow a specific order for cell division to be successful. The correct sequence for these events starts with the kinetochore becoming attached to the mitotic spindle. Following that, sister chromatids line up at the metaphase plate. After alignment, the cohesin proteins that hold sister chromatids together break down and the sister chromatids separate. Finally, the cell reorganizes its contents, the nucleus reforms, and the cell divides (cytokinesis). The correct order thus is option d, matching the chronological process during mitosis.