Question

In sickle-cell anemia, the primary, but not secondary or tertiary structure of hemoglobin, is affected.

A. True
B. False

Answer 1

In sickle-cell anemia, the primary structure of hemoglobin is affected.

Step-by-step explanation:

A. True

In sickle-cell anemia, the primary, but not secondary or tertiary structure of hemoglobin, is affected.

The primary structure of a protein refers to the unique sequence and number of amino acids in a polypeptide chain.

In the case of sickle-cell anemia, a change of glutamic acid with valine in the sixth position of the beta chains of hemoglobin causes the red blood cells to change shape, leading to the symptoms of the disease.