Final answer:
When a metabolic block occurs in a biochemical pathway, the amount of the substance immediately prior to that block usually increases due to feedback inhibition.
Step-by-step explanation:
When a metabolic block occurs in a biochemical pathway, it is true that the amount of the substance immediately prior to that block usually increases. This is because the block prevents the normal flow of the pathway, causing the substrate to accumulate.
This is known as feedback inhibition and it helps regulate the rate of production of the substance.