Final answer:
Phospholipase C and inositol phospholipid are both involved in cellular signaling and act as second messengers. Phospholipase C cleaves PIP₂ to form DAG and IP3, while inositol phospholipids can be phosphorylated to form PIP and PIP₂.
Step-by-step explanation:
Phospholipase C and inositol phospholipid are both involved in cellular signaling and act as second messengers. Phospholipase C cleaves phosphatidylinositol bisphosphate (PIP₂) to form diacylglycerol (DAG) and inositol triphosphate (IP3). DAG remains in the plasma membrane and activates protein kinase C (PKC), while IP3 diffuses into the cytoplasm and binds to calcium channels to release Ca²+.
On the other hand, inositol phospholipids, such as phosphatidylinositol (PI), are present in small concentrations in the plasma membrane. They can also be converted into second messengers. Enzymes known as kinases phosphorylate PI to form PI-phosphate (PIP) and PIP₂, which are involved in various cellular signaling pathways.