Final answer:
Nucleosomes coil into a 30-nm chromatin fiber, which further condenses into chromosomes, the most condensed form of chromatin observed during cell division.
Step-by-step explanation:
Nucleosomes are organized into a more compact structure known as a 30-nm chromatin fiber. This occurs when the nucleosomes and the linker DNA between them coil into the second level of compaction. This coiling, which includes the interaction with more non-histone proteins, allows the chromatin to condense into chromosomes, which are the most condensed form of chromatin, especially evident during the metaphase stage of mitosis.