Final answer:
The most complete and accurate statement about MAPs is that they stabilize microtubules and prevent their depolymerization, and organize them into bundles and networks, aiding in maintaining cell shape, division, and transport.
Step-by-step explanation:
The most complete and accurate representation of MAPs (Microtubule-Associated Proteins) concerning their contribution to cytoskeletal structure and function in vivo is: MAPs stabilize microtubules and prevent depolymerization, and MAPs organize microtubules into bundles and networks.
Microtubule-Associated Proteins have several crucial roles in cellular activities related to the cytoskeleton. They do contribute to the nucleation of microtubules, and while they are not involved in the sliding of microfilaments in muscle contraction, that role is specific to the interaction between actin microfilaments and motor proteins like myosin. MAPs particularly stabilize microtubules by binding to them, which can protect microtubules from depolymerization, thus providing structural support and making them less dynamic. Additionally, MAPs also play a part in organizing microtubules into bundles and networks, which is essential for their role in maintaining cell shape, cell division, and intracellular transport.