Final answer:
The Dobzhansky-Muller model explains hybrid infertility between close species as a result of epistatic interactions between alleles of different loci.
Step-by-step explanation:
The Dobzhansky-Muller model explains hybrid infertility in crosses between two close species.
It posits that epistatic interactions between the alleles of two or more loci, undergoing different evolutionary paths in the two speciating groups, lead to the fitness costs of hybridization.