Question

A researcher creates a cell line in which thymosin beta4 is overexpressed. Which of the following would you expect to see in this cell line?

A. Increased microtubule stability
B. Increased actin filament stability
C. Enhanced nucleation of microtubules
D. Decreased polymerization of actin filaments

Answer 1

Overexpressing thymosin beta4 in a cell line is likely to result in increased actin filament stability, enhancing cell motility and wound healing.

Step-by-step explanation:

Thymosin beta4 is a protein involved in cell motility and wound healing. When thymosin beta4 is overexpressed in a cell line, it can affect the stability and dynamics of the cytoskeleton. Specifically, overexpression of thymosin beta4 is likely to result in increased actin filament stability. Actin filaments are important for maintaining cell shape and allowing cells to move and change shape, so increased stability of actin filaments would likely enhance cell motility and wound healing.