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What would be the effect of a mutation in the RAS gene that inactivates its GTPase function?

User Sarah
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Final answer:

A mutation in the RAS gene that inactivates its GTPase function leads to uncontrolled cell proliferation and the potential development of cancer.

Step-by-step explanation:

A mutation in the RAS gene that inactivates its GTPase function would have a significant effect on downstream cellular events. The RAS protein acts as a molecular switch that controls cell growth, differentiation, and survival by cycling between an active GTP-bound form and an inactive GDP-bound form. When the GTPase function is inactivated, the RAS protein remains in its active state for a longer period of time, leading to uncontrolled cell proliferation and the potential development of cancer.

User Chevone
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