Final answer:
The false statement is e. The intrinsic apoptotic pathway amplifies the signal by a caspase cascade while the extrinsic pathway uses a different amplification method. Both intrinsic and extrinsic apoptotic pathways use a caspase cascade to amplify the signal.
Step-by-step explanation:
The student's question is focused on determining which statement is false regarding the mechanisms of apoptosis, also known as programmed cell death. Let's analyze each statement one by one:
- a. Activation of apoptosis from signals inside the cell is part of the "intrinsic apoptotic pathway": This statement is true. The intrinsic pathway is triggered by internal signals, often due to cellular stress or damage, leading to the release of cytochrome c from mitochondria.
- b. Cells normally contain a "death receptor" that can be activated by a lymphocyte if it detects abnormalities in the cell: This is true. Death receptors are part of the extrinsic apoptotic pathway and can trigger apoptosis in response to signals from immune cells like lymphocytes.
- c. Apoptosis can be triggered by extracellular signals to activate the "extrinsic apoptotic pathway": This is also true. The extrinsic pathway is initiated by external signals such as those from death receptors.
- d. Cytochrome C is released from mitochondria during activation of the intrinsic apoptotic pathway: This statement is true and it's a key step in the intrinsic pathway.
- e. The intrinsic apoptotic pathway amplifies the signal by a caspase cascade while the extrinsic pathway uses a different amplification method: This is the false statement. Both the intrinsic and extrinsic apoptotic pathways eventually amplify the apoptotic signal through a caspase cascade.