Question

. Which of the following is NOT true about Bcl-2 family members:

a. Bcl-2 family members can be pro-apoptotic.
b. Bcl-2 family members trigger entry into S phase.
c. Bcl-2 family members form dimers.
d. Bcl-2 family members can be anti-apoptotic.
e. Bcl-2 family members can form channels in the mitochondria.

Answer 1

Bcl-2 family members do not trigger entry into S phase. Hence the correct answer is option B

Step-by-step explanation:

The correct answer is b. Bcl-2 family members trigger entry into S phase.

The Bcl-2 family of proteins are a group of regulatory proteins that control the process of programmed cell death, or apoptosis. They play a crucial role in the regulation of apoptosis by either promoting or inhibiting cell death.

Some members of the Bcl-2 family, such as Bax and Bak, are pro-apoptotic and promote cell death. They work by forming channels in the mitochondria, allowing the release of cytochrome C into the cytoplasm, which triggers a cascade of molecular events leading to apoptosis.

On the other hand, some members of the Bcl-2 family, such as Bcl-2 itself, are anti-apoptotic and inhibit cell death. They prevent the release of cytochrome C and block the apoptotic pathway.

However, Bcl-2 family members do not trigger entry into S phase. Entry into S phase is primarily regulated by cyclins and cyclin-dependent kinases (Cdks), which control the progression of the cell cycle.

Hence the correct answer is option B